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OS-RC-2, 786-O and MIHA cells were cultured in RPMI-1640 medium supplemented with 10% FBS and 1% P/S at 37 C with 5% CO 2

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10.1134/S0006297924603976 50 HaddadzadeganS.DorkooshF.Bernkop-SchnurchA

Liver tissues were further analyzed to observe changes in lipid accumulation

Immunoassays performed in the mouse model of APAP toxicity determined the relationships between tissue adducts and toxicity, as measured by pathologic examination of the liver tissues and serum ALT levels (Potter et al