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Risk factors for nonalcoholic steatohepatitis include age older than 45 years, an aspartate transaminase (AST) level greater than the alanine transaminase (ALT) level, diabetes, insulin resistance, low albumin level (less than 3.6 g per dL [36 g per L]), low platelet count (less than 100 10 3 per L [100 10 9 per L]), metabolic syndrome, obesity, and portal hypertension on imaging

One theoretical consideration is that both compounds may influence gastrointestinal function