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Vitamin B12 deficiency and pernicious anaemia Peer reviewed by Dr Doug McKechnie, MRCGPLast updated by Dr Colin Tidy, MRCGPLast updated 5 Jul 2024 DownloadDownload Share Language Discussion Audio Version Add to preferred sources on Google In this series:AnaemiaDiets suitable for people with anaemiaFolic acid deficiencyIron-deficiency anaemiaMacrocytosis and macrocytic anaemia Vitamin B12 is essential for life

It also affects the parietal cells in stomach (parietal cells produce gastric acid to aid digestion of food) through the production of antiparietal cells antibodies results in chronic failure of gastric acid production

Levels can quickly deplete in 10 to 20 days

Some studies have found that low levels of vitamins B9 or B12 may indicate a higher migraine risk, while in some cases, supplementation with B vitamins has improved migraine frequency or severity