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Description

Int J Mol Sci 23:9566

These are one of, if not the most rigorously studied class of peptides ever, with many large, placebo-controlled, randomized trials that followed over the past twenty years from the original GLP-1 drugs such as exenatide, approved by the FDA in 2005

They arent exotic in themselves

Its structure incorporates specific amino acid substitutions to enhance solubility and prevent fibril formation, along with the addition of a C18 fatty diacid moiety via a linker