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The World Health Organization estimates that cataracts in up to 20% of the people who become blind annually may be caused or enhanced by sun exposure ( Figure 1A ) and subcapsular cataract ( Figure 1C ) ( Figure 1B ) ( Epidemiological studies have shown that higher rates of cataract are observed in populations that spend more time outdoors ( Brunescence, the process of progressive pigmentation of the aging human lens which turns a young, colourless lens increasingly yellow, brown and even black, has been specifically linked to UV exposure ( 1.3 Lens UV exposure protection mechanisms The young lens contains several tryptophan metabolites, which act as UV filter compounds that absorb light in the 300 to 400 nm wavelength range (92)

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