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M-cells take up large antigens, macromolecular complexes, particulates, and proteins such as ferritin and peroxidase and also intact viruses, bacteria, and protozoa through a specific and regulated process termed receptor-mediated endocytosis in which cell-surface receptors such as GP2 recognize specific antigens expressed on microorganisms that initiate transit through the cell, exocytosis, and engulfment by phagocytic subepithelial dendritic cells (Fig

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m o ) Representative whole dorsal striatal images of SST immunofluorescence from Trkb Penk-WT control ( m ), Trkb Penk-KO mutant injected at 3 M with Gsto2 -shRNA ( n ) or scrambled-shRNA in the striatum ( o ) and analysed at 15 W