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Noonan JE, Jenkins AJ, Ma JX, Keech AC, Wang JJ, Lamoureux EL

doi: 10.1021/bi0258795

Practical strategies to circumvent the toxicity issues of UCNPs include the fabrication of ultra-small nanoparticles to increase biological elimination, surface functionalization with bio-biocompatible ligands or detoxifying reagents, and enhancement of the upconversion efficiency of UCNPs to decrease light dosage in practice

Quercetin and quercetin-3-O-glucuronide are equally effective in ameliorating endothelial insulin resistance through inhibition of reactive oxygen species-associated inflammation