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Studies suggest that intrinsic resistance can be caused by (a) inherited genetic alterations that result in most of the tumor cells having reduced responses to chemotherapy and target drugs

Short-term decreased physical activity with increased sedentary behaviour causes metabolic derangements and altered body composition: effects in individuals with and without a first degree relative with type 2 diabetes

Compared to plasma and control arteries, stable plaques have increased CE containing polyunsaturated fatty acids (170), which have increased susceptibility to oxidation