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[DOI] [PubMed] [Google Scholar] 67.St S, Zorolu SS, Ozyurt H, et al

Cancer cells use precursors derived from the TCA cycle intermediates to synthesize proteins, lipids, and nucleic acids

bilis and is seen following treatment with various hepatocarcinogens

In addition to conferring protection against HFD-mediated alteration in glucose metabolism, the NQO1 transgenesis also imparts improvement of lipid metabolism, as indicated by decreased abundance of lipotoxic species (e.g., ceramide, MAGs, DAGs) (Fig