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The ribosomal protein S6K is activated by mTORC1, which increases protein synthesis

Kleschyov et al., 2012

2224 Aldehyde dehydrogenase can also play a significant role in moderating activity by converting aldophosphamide to the inactive carboxyphosphamide metabolite, which accounts for about 80% of the cyclophosphamide dose excreted in the urine