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Accordingly, an association between the SNP rs2631365-TC located in the promotor region of OCTN2 and failure of imatinib treatment has been described (Jaruskova et al., 2017)

One of the oldest references to a DDT formula I could find is from the Journal of Industrial and Engineering Chemistry, Vol 12 (1920)(p

Definition of hyperprogression Hyperprogression was defined using the previously established criteria for solid tumors as progressive disease in the first 8 weeks after treatment initiation, a 10 mm minimum increase in the measurable lesions, plus: (i) an increase of 40% in the sum of target lesions compared with baseline and/or (ii) an increase of 20% in the sum of the target lesions compared with baseline plus the appearance of new lesions in at least two different organs