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10.2165/00003088-198713050-00001 67 HongM.HanD

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One study reported a nonsignificant positive trend in the correlation between the magnitude of decrease in IGF-I levels and the magnitude of decrease in cortisol levels in 78 patients with MDD during 6 weeks of antidepressant treatment 39

It inhibits the growth of GBM and medulloblastoma cells exhibiting variable radio-responses and TP53 mutations by arresting the cell cycle (G 2 /M phase)