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It is not recommended by NICE and has no MHRA-licensed indication for this use

Donor and collection related factors can affect the concentration of HSPC in the resulting cellular product and the harvesting physician frequently requests evaluation of the quality of the BM harvest during the procedure

Furthermore, it regulated the expression of purinergic receptors (including A2A, A3, P2X4, P2X7, and P2Y1), which are recognized for their significant roles in the inflammatory response associated with DED [77]