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Reading the unique DNA methylation landscape of the brain: non-CpG methylation, hydroxymethylation, and MECP2

Sapmaz et al., 2022)

While there are different models to study glutathione metabolism, in this study we used BSO as it is a specific and potent chemical inhibitor of the rate limiting enzyme GCLC (38)

Chronic alcohol feeding combined with multiple high-dose alcohol gavages can simulate the drinking patterns of most patients with liver disease and are highly similar to the pathogenesis of human ALD