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Inhibition of glutamine synthetase can trigger the conversion of M2-like TAMs to the more inflammatory M1-like phenotype, thus impeding tumor metastasis (77, 78)

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3.2.6 Treatment of other systemic diseases Myocardial infarction (MI), an acute cardiovascular emergency, is primarily treated by curtailing the progression of myocardial necrosis and promoting functional recovery (Lu et al., 2015)