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172 This suggests that the regulatory role of JNK in macrophage activation may also be relevant in the context of PAH

Notably, 176 regions that were hypomethylated in cancer were remethylated after curcumin treatment, including the tumor necrosis factor (TNF) gene, suggesting a reversal of tumor-associated epigenetic changes

Compromised intestinal barrier integrity is observed in both intestinal and systemic diseases, including IBDs, autoimmune diseases, and other metabolic diseases 83