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76 For instance, AARS1 functions as an intracellular lactate sensor, directly binding lactate to form lactate-AMP, and mediates lactylation of K120/139 on p53 within its DNA-binding domain (DBD), which prevents the binding of p53 to DNA containing p53 response elements (p53RE-DNA) and subsequent p53 liquidliquid phase separation (LLPS)

Boars, One injection 1-2 weeks prior to breeding season

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By continuing to explore the intricate connections between glutathione, redox signaling, and autism, researchers aim to develop targeted interventions and treatments that address the underlying mechanisms of autism and improve the quality of life for individuals affected by this condition