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Thymosin Beta-4 itself is naturally present at high concentrations in platelets and at lower concentrations across many tissues

Further, the extraordinary affinity of HGF for Dihexa (Kd=2.2 x 10 "13 M) suggests that normally non- biologically active levels of HGF become physiologically relevant in the presence of a high affinity mimetic

K: Lysine

Skin Repair Pathways MMP/TIMP, Collagen & Elastin (PMC, 2015) A focused review of GHK as a modulator of multiple skin regeneration pathways published in PMC confirmed that GHK-Cu stimulates both synthesis and breakdown of collagen and glycosaminoglycans, and modulates the activity of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs)