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A global observational clinical study of HD has assessed the effects of metformin on cognition, with linear analysis finding that metformin was related to the better cognitive ability of patients with HD ( Animal experiments have shown that metformin can prolong the survival time of HD transgenic male mice ( via the MID1/PP2A complex and reduced S6 phosphorylation, which completely restored the mices early network activity pattern and behavioral abnormalities

Combining a stopped-flow system with a dynamic light scattering apparatus allowed for reduction of the time-resolution of the method to the order of 1 s (Gast et al., 1997)

Mu, J., Lam, S

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