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Buffers are frequently added to parenteral formulations to optimize solubility and stability by adjusting the pH

FIGURE 1 2.1 Lipid metabolism and ferroptosis induction in melanoma Ferroptosis is closely linked to dysregulated lipid metabolism in melanoma, in which polyunsaturated fatty acid (PUFA) metabolism serves as the central molecular mechanism

(184 L) of the reaction solution was taken and incubated with N-acetyl-cysteine methyl ester (7.4 mg, 6 equiv.) at 37 C for 30 min in 5 mL of acetonitrile and 1 mL of water

3.8.3 Glyphosate Glyphosate is a widely used herbicide acting via inhibition of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase, which blocks the shikimate pathway responsible for synthesizing aromatic amino acids including phenylalanine, tyrosine and tryptophan (Chiantia et al., 2025)