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Most people get enough B12 from their diet, but many have absorption issues that mean adequate intake doesnt translate into adequate cellular levels

However, sustained release systems introduce new challenges with once administered, depot formulations cannot be easily reversed in cases of hypersensitivity or adverse drug reactions

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These results suggest that the inflammatory injury in the intestine elicits an increase in E-GPx in the plasma that is associated with an increase in E-GPx mRNA in the kidney