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Antibacterial activity of curcumin via apoptosis-like response in Escherichia coli

These pathways are activated in response to OS, leading to apoptosis and inflammation, further contributing to neurodegeneration

However, at the same time, iron overload interferes with the fusion of autophagosomes with lysosomes and inhibits lysosomal acidification and hydrolase activity, thereby blocking the autophagy process [67, 68] (Fig