Research background
No effect was observed on holoTC and methylmalonic acid concentrations
Analysis of the nanobody binding interface with protein interfaces, surfaces, and assemblies (PISA 20 ) demonstrates a solvation-free energy gain of 10.3 kcal/mol, with an interface area of 772 2
CRP1386903A 204612 EXCL-NPF-26 (08/08/2025) Page 5 Drug Class Excluded Medications Preferred Alternatives CONZIP, QDOLO, TRAMADOL 25MG & 75MG TABLETS, TRAMADOL ER CAPSULES, TRAMADOL SOLUTION tramadol 50mg & 100mg tablets, tramadol er tablets hydromorphone tablets, morphine tablets, oxycodone tablets, oxymorphone tablets hydrocodone/acetaminophen, morphine sulfate, oxycodone, tramadol, tramadol/acetaminophen hydrocodone bitartrate er, hydromorphone er, morphine sulfate er, oxymorphone hcl er, HYSINGLA ER levorphanol AUTONOMIC & CENTRAL NERVOUS SYSTEM (continued) Narcotic Analgesics & Combinations NUCYNTA NUCYNTA ER, OXYCODONE ER, OXYCONTIN, XTAMPZA ER OXAYDO, OXYCODONE COATED TABLETS, ROXYBOND oxycodone uncoated tablets PRIMLEV, PROLATE SOLUTION oxycodone/acetaminophen SEGLENTIS tramadol 50mg tablets plus celecoxib Narcotic Antagonists Niemann-Pick Disease Type C Agents Rett Syndrome Agents ZIMHI naloxone syringes MIPLYFFA AQNEURSA DAYBUE No alternatives recommended DORAL, QUAZEPAM estazolam, lorazepam Sedative-Hypnotic Agents ZOLPIDEM 7.5MG CAPSULES eszopiclone, zaleplon, zolpidem tablets citalopram tablets, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, vilazodone desvenlafaxine er, duloxetine, venlafaxine hcl er, FETZIMA Selective Serotonin Reuptake Inhibitors (SSRIs) Antidepressants Serotonin/Norepinephrine Reuptake Inhibitor Antidepressants CITALOPRAM CAPSULES DRIZALMA SPRINKLE, VENLAFAXINE BESYLATE ER FENTANYL CITRATE BUCCAL TABLETS, FENTORA Transmucosal Fentanyl Analgesics fentanyl citrate lozenges APLENZIN, BUPROPION XL 450MG, FORFIVO XL bupropion xl 150mg or 300mg RALDESY trazodone tablets Miscellaneous Antidepressants olanzapine/fluoxetine, bupropion, desvenlafaxine er, duloxetine, escitalopram, mirtazapine, sertraline tablets SPRAVATO CARDIOVASCULAR ACE Inhibitors QBRELIS lisinopril Alpha-Adrenergic Agonists CLONIDINE ER 0.17MG, NEXICLON XR clonidine patches, clonidine tablets candesartan, irbesartan, losartan, olmesartan, telmisartan, valsartan EDARBI candesartan/hydrochlorothiazide, irbesartan/hydrochlorothiazide, losartan/hydrochlorothiazide, olmesartan/hydrochlorothiazide, telmisartan/hydrochlorothiazide, valsartan/hydrochlorothiazide, chlorthalidone plus valsartan Angiotensin Receptor Blockers (ARBs) & Combinations EDARBYCLOR (continued) 2025 Evernorth Health Services
