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Continuous Monitoring: Alerting to changes that might indicate compromise

Cell 115:787798 Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

In summary, TFAM protein abundance is closely related to mtDNA content, and TFAM affects mitochondrial biosynthesis by regulating mtDNA copy number through its interaction with mtDNA (Picca and Lezza, 2015)