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Food Chem 131:247258 Schauss AG, Beres E, Vertesi A et al (2011) The effect of ergothioneine on clastogenic potential and mutagenic activity: genotoxicity evaluation

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PMID: 23524842

Participants with orthostatic hypotension (defined as a decrease of 20/10 mmHg in systolic/diastolic blood pressure upon standing) with no cognitive impairment at baseline had a 40% increased risk of developing dementia during 12 years of follow-up, and those exhibiting cognitive impairment had a 54% increased risk of progression to dementia