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Warning signs include: Severe, persistent abdominal pain that may radiate to the back Nausea and vomiting that does not resolve Abdominal tenderness or distension Patients experiencing these symptoms should discontinue tirzepatide immediately and seek emergency medical evaluation

Although ferroptosis is morphologically and biochemically distinct, its regulators (e.g., GPX4, Nrf2, DHODH) overlap with those in other oxidative death pathways, raising questions about its uniqueness in BPD