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Association between microbiota-dependent metabolite trimethylamine-N-oxide and type 2 diabetes

Recently, this technique has been used to design polysuccinimide-based nanoscaffolds activated with ethylene diamine to address the decoration with oxidized EGCG (green tea polyphenol epigallocatechin-3-gallate): as a result, an improvement in the extracellular and intracellular anti-amyloidogenic effect of EGCG was detected, highlighting the potential of these nanocarriers compared to the administration of EGCG in its free molecular form in the prevention and curing of amyloid derived diseases (Debnath et al., 2016)

Quantitative Analysis of the Substrate Specificity of Human Rhinovirus 3C Protease and Exploration of Its Substrate Recognition Mechanisms

There is also formal clinical investigation, including the cystic fibrosis trial noted earlier