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Several authors suggest that oxidative damage leading to neuronal degeneration may explain the irreversibility of TDS (41, 42)

(6) Pickart L, Vasquez-Soltero JM, Margolina A

The result is higher glutathione availability, improved removal of reactive species, and reinforced repair/clearance pathwaysstrengthening resilience without completely shutting down physiological redox signaling (Andrs et al