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Furthermore, copper can modulate tau pathology by inhibiting GSK3 via Akt signaling, reducing tau phosphorylation and potentially mitigating NFT formation

Park DJWS, Yun WC, Kim J-E, Park SH, Lee S, Ha JS, Choi J, Key YJ, Seo

As already said, most of the GSTUs display their highest expression levels in roots, however, GSTU4, 9, 15 , and 16 are exclusively and strongly expressed at the siliques/seeds stages