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Unfortunately, the clinical experience, although encouraging, is based on results obtained from small patient groups, short follow-up periods and studies without control conditions, so the results cannot be considered conclusive

Its strong expression might therefore be caused by a more distal regulatory mutation

Mechanisms involved in the antinociception caused by melatonin in mice

By examining the pH values of media containing 0.5 mM glucose with a titration of lactic acid (0-20 mM), we found that the pH of 20 mM lactic acid was much closer to reported inner pH of solid tumor (Figure S1A)