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Plos Pathogens 12 , e1005591, (2016)

Retrieved 3 May 2023

Specifically, analyzed were the affected brain areas (04), cerebral (NTP-7, Level 3), cerebellar cortex (NTP-7, Level 6), and hippocampus, thalamus, and hypothalamus (NTP-7, Level 3) as follows (score 0 indicates no histopathologic change): score 1: small, patchy, complete, or incomplete infarcts (10% of the area affected)

This finding suggests that inhibition of Akt phosphorylation would paradoxically lower fibro-adipogenic depositions but also decrease endogenous compensatory mechanisms and overall muscle function