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10.1371/journal.pone.0060074 5 AhmedS.UllahN.ParveenS.JavedI.JalilN

[4] Note: as previously mentioned, the lipoyl-lysyl arm, arranged in an extended conformation and able to access the active site of pyruvate dehydrogenase where TPP is bound, enables the transfer of the acetyl group, generated by oxidation of hydroxyethylTPP, to the lipoamide moiety