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(PubMed) Schurgers LJ, Teunissen KJ, Knapen MH, et al

However, randomized controlled trials of only oral thiamin supplementation have not found any benefit in CHF patients

Jackson G, Arver S, Banks I, Stecher VJ

From six months to one year of use, the percent of patients who experienced at least 75% of repigmentation on their face increased from 30% to nearly 50%