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As a System X c inhibitor, Sorafenib is the only anticancer drug that causes ferroptosis in patients with HCC (Louandre et al., 2013)

En la etapa proteoltica final de la cascada, el fibringeno se escinde proteolticamente por trombina a fibrina, que a continuacin se reticula en el sitio de la lesin para formar un cogulo.As used herein, the coagulation pathway or coagulation cascade refers to the series of activation events that leads to the formation of an insoluble fibrin clot

Mitochondrial DNA damage in Iron overload [J]

Unlike DAMPs, which are not derived from infectious pathogens and initiate infection-related inflammation, PAMPs originate from the invasion by foreign substances and infections caused by microorganisms or viruses (Hemmi et al., 2000)