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[31] reported that Mexican subjects with rs694539 variation (genotype AA, recessive inherence model) in the NNMT gene sequence have lower BMI values

usually more prevalent in younger adults or children

Not validated for clinical, diagnostic, or therapeutic use

Using 3D bioprinting technology, Kim and coworkers developed a cancer-on-a-chip to mimic the TME and predict effects of immunotherapeutic agents ( 3.4 In-depth investigation of immunological mechanism The dynamics and heterogeneity of immunosuppressive mechanisms in TME are major reasons for the failure of tumor vaccines and other immunotherapy strategies