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Deficiency can impair thyroid hormone metabolism, increase the risk of infections, and contribute to cardiomyopathy (Keshan disease), skeletal abnormalities (Kashin-Beck disease), and chronic inflammation

doi: 10.1016/j.actbio.2016.02.028

Lee DW, Q-S Z, Rudra S, Shpall EJ, Kornblau SM , Corey SJ

Numerous studies have demonstrated that conditions such as obesity, diabetes, and certain surgical procedures can result in nephron hypertrophy, primarily characterized by the enlargement of both glomeruli and tubules