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Her outcome was visibly positive, but the maintenance cadence we recommended was slightly tighter than the standard schedule, which she budgeted for upfront after we showed her the annualised cost rather than discovering it at month nine

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To achieve tHcy concentrations as low as possible ( C mutation in the MTRR gene creates an SF2/ASF binding exonic splicing enhancer, which leads to pseudoexon activation and causes the cblE type of homocystinuria

The dose of vitamin B12 injection for adults may vary depending on the problem to be treated: Treatment of mild nerve pain : the initial dose is 5,000 IU until pain resolves Treatment of intense nerve pain: the initial dose can be increased to 15,000 IU per day and reduced by the doctor as pain resolves Treatment of pernicious anemia: the dose can vary from 100 to 1000 IU per day and the treatment time varies from person to person