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Main histological changes of ATN are: merging and loss of tubular epithelial cells, focal dilatation of proximal tubules, partial occlusion of tubular lumens by cellular debris and multiple mitoses

HD1914 with a Cys : Met ratio of 4.0

134, e1775, 10.1542/peds.2014-2986 60 ParkS

In a cellular model, steatosis was induced in Hep2G cells by exposing them to oleic acid and co-culturing them with vitamin C, N-acetylcysteine, and ASTX