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We recognize the critical need for future studies to validate these using human-derived cell lines and PDX models to confirm the translational significance of our results, and are developing and testing strategies for utilizing immunodeficient mice for studies of obesity and cancer [40]

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In addition, ten genes (such as anti-ACSL3 antibody (ACSL3), GPX4, and SLC7A11) associated with ferroptosis have been postulated to have regulatory roles in lung adenocarcinoma (15)

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