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The PRISMA checklist has been included as Supplement Table 1

Urol Sci 31:56 Abdulhadi MH, Al-Kuraishy HM, Al-Gareeb AI (2021) Beneficial effects of levothyroxine replacement therapy on leptin adiponectin ratio in patients with idiopathic primary hypothyroidism

However, complex virulence mechanisms and metabolic adaptations have evolved from enteric pathogens to successfully compete with symbiotic microorganisms and access to the niches for infection in mammals (Pifer and Sperandio, 2014)