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The critical knowledge gaps persist in defining optimal stress thresholds by adjusting dosing intervals and in modeling subpopulation dynamics (sensitive/tolerant ratios, proliferation kinetics) that govern tumor adaptation

and found that the ethanolic extract was more effective against Anopheles mosquito larvae than the acetone extract, with LC 50 values of 185.99 ppm and 148.05 ppm after 24 and 48 h, respectively

Although not yet applied clinically in AD or PD, such strategies suggest that systemic NPs can reprogram microglia via gene or cytokine delivery

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