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Kidney pain is more likely to be severe, one-sided, and accompanied by other symptoms like fever, nausea, burning with urination, or blood in the urine

In contrast, serum ELISA antibody tests detect only immune sensitization, indirect evidence that cannot confirm current or ongoing exposure, and they lack validation for exposure assessment

Therefore, it is crucial to elucidate the composition of trace elements in cardiovascular diseases relative to physiological levels and provide valuable insights into treatment strategies for cardiovascular diseases