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doi: 10.1016/j.annepidem.2024.10.006 18

5 :e306 42

4-HNE generation negatively impacts on meiotic competency Having established that the levels of 4-HNE are significantly elevated upon exposure of oocytes to H 2 O 2 , we next sought to determine the impact of this signature of enhanced OS on the meiotic competency of oocytes