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Description

The extremely slow and variable activity of dihydrofolate reductase in human liver

DDX11-AS1 was distributed both in the nucleus and the cytoplasm of HCC cells

Interestingly, acidification of endosomes, by specific inhibitors or by genetic deletion of the endosome-specific sodium-hydrogen exchanger 6 (NHE6), not only restored plasma membrane apoER2 levels but also suppressed amyloid deposition even in the absence of apoE4 [228]