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Conversely, granulosa cells show reduced GPx4 expression and ferritinophagy-mediated iron overload, leading to heightened susceptibility to ferroptosis and impaired oocyte quality ( Therapeutic approaches targeting these pathways have been explored

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein

One patient discontinued because of an ISR in the 21-day study, and 2 patients in the 21-day study discontinued because of akathisia

While tirzepatide preserves lean mass better than diet alone, some researchers look for ways to further protect muscle during aggressive weight loss