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Women in their 60s and beyond experience thinning of the skin (fragile dermis, age spots, and bruises become more noticeable) with delayed wound healing, along with reduced ability to sense touch, pressure, temperature, etc

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Conversely, neuroprotective microglia activated by IL-13, IL-10, and IL-4 secrete various factors associated with neuroprotection and tissue repair, including TGF-, Chi3l3, Arginase 1, Ym1, IGF-1, and Fzd1 (48)