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Allergic reactions: Rarely, ingredients such as methionine or preservatives may cause an allergic reaction including itching, rash, or breathing difficulty

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In addition, the individual metabolite concentrations were used to calculate the ratios of betaine: choline and DMG: betaine, as well as total homocysteine (homocysteine and homocystine) and total cysteine (cysteine and cystine) contents

Meanwhile, probiotics, prebiotics and synbiotics have also been studied for their ability to modulate oxidative stress and antioxidant defense mechanisms in fish, highlighting their multifaceted health benefits