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The complex FF environment is made up of a wide range of complex substances released by oocytes, granulosa cells, and theca cells, such as proteins, RNAs, and metabolites [499,500,501,502,503]

Furthermore, homocysteine can be converted back into methionine through the utilization of betaine, a metabolite of choline, which acts as a methyl donor in a reaction catalyzed by betaine homocysteine methyltransferase (BHMT)

Glutathione which is a tri-peptide of 3 amino acids (glutamic acid, cysteine and glycine) plays an important role in liver detoxification, also known as the bodys master antioxidant

We thank the NSF (CHE0619339, CHE 0443618) for the 500 MHz NMR and the high-resolution mass spectrometer used in this work