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Lysosomal dysfunction, whether through altered pH, reduced enzymatic activity, or defective membrane transport, further limits payload activation and effective drug release

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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Xia C, Tao Y, Li M, Che T, Qu J

And, in our investigation, we corroborated that T-bet expression in colorectal cancer tissues was significantly diminished compared to normal tissues and was inversely related to TNM stage