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402 Resveratrol protects the heart from I/R injury and cardiomyopathy through multiple mechanisms, such as scavenging free radicals, reducing myocardial oxygen demand, inhibiting inflammation-induced damage, inducing angiogenesis, improving mitochondrial function, and preventing cardiomyocyte apoptosis

Creating a treatment plan that fits each person is vital

In in vitro assays using peripheral blood mononuclear cells from patients with AS, it was demonstrated that cryptotanshinone and tanshinone IIA, the main compounds of SMR, significantly reduced the protein expression levels of COX-2, IL-6, and TNF-

Also preferred is an isolated nucleic acid molecule comprising a nucleotide sequence which is at least 95% identical to a sequence of at least 50 contiguous nucleotides in the nucleotide sequence of a cDNA clone identified by a cDNA Clone Identifier in Table I, which DNA molecule is contained in the deposit given the ATCC Deposit Number shown in Table I